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References - Pharmaceuticals, NRT

A page listing references to pharmaceutical industry topics, pharmaceuticals and NRTs.

The section on pharmaceutical industry criminal convictions became so large it was moved to its own page - see menu at right.

 

Chantix - the 'murder drug'

Pharmaceutical interventions for smoking cessation fall into two categories: psychoactive (or psychotropic) drugs and NRT. The psychoactive drugs have different operational functions on the brain, and NRTs contain one or other of the numerous alkaloids in tobacco. While NRTs are among the safest drugs of all (since they are simply a megadose nutritional supplement if the active ingredient is nicotine), the psychoactive drugs have an extremely poor safety record. The  distributors have paid billions in fines and damages for injury caused by these drugs. Varenicline especially (Chantix, Champix) has a terrible reputation; many smokers can tell you how they had thoughts of killing themselves and even their families while taking it; and enough of them went through with it that Chantix is regarded as the most dangerous prescription drug available. It was removed from the prescription list in France for this reason - a rare event.

1. Dr D Healy on how Chantix promotion kills, May 2014:
http://davidhealy.org/motivational-interviewing/

2. Mental health issues with Chantix and Zyban
http://center4research.org/medical-care-for-adults/depression-stress-and-mental-health/drugs-to-quit-smoking-chantix-and-zyban-can-affect-mental-health/

3. Chantix user comments
https://vapinglinks.wordpress.com/2015/02/08/vaping-over-drugs-like-chantix-zyban-why-we-need-a-choice-a-vaping-rant-vaping-voices/

4. Varenicline-Induced Parkinson's Disease
http://archive.hospital-pharmacy.com/doi/abs/10.1310/hpj5007-564

 

NRT

1. NRT success rate 0.8% at 12 months:
http://tobaccoanalysis.blogspot.co.uk/2010/03/new-study-shows-that-even-extended.html
 

NRTs - harm

1. Concomitant use of cessation therapies and smoking appears harmless:
http://www.treatobacco.net/en/page_70.php
[the word 'ecigs' or 'ecigs and NRT' could be substituted for 'NRT' in this paper without any substantive alteration of the facts]

 

Children poisoned by NRT

It is legal to give NRTs to children over 12 in the UK. Therefore, anti-smoking groups distribute nicotine-containing drugs to children as young as 12 in British schools without knowledge of the parents and without permission (and according to the schools, apparently without their permission either; although this may be a statement made to avoid liability). Several incidents have occurred where children have been hospitalised or sent home ill as a result. So far it appears that no parent has sued for assault on a child by such agencies, but the UK is by and large not a litigious society. Since it is apparently legal for these agencies to act in this way, criminal prosecutions seem unlikely. Of course, one argument is that nicotine is harmless in any case and giving overdoses to young children is perfectly acceptable for public health purposes. This illustrates a double standard: nicotine is harmless and virtually tax-free when given in overdose quantities to young children by government-funded agencies; but deadly dangerous, addictive, highly toxic and subject to supertax when used by anyone else. Which is it?

It also raises numerous questions: can the public health industry therefore supersede any legal duty of care to children? Can they freely assault children without redress? Can they enter schools and assault children without either the school or parents knowing? Could they, for example, spray children with CS gas to put across the message that people should not attend street demonstrations as it may be unhealthy? Is the public health industry, in fact, completely above the law? (Or at least the law as most people understand it: responsible actions that do not harm others, and that assigns an extra duty of care to all with regard to children; not the special version of the law that seems to apply to the public health industry.)

1. http://www.telegraph.co.uk/news/health/news/9823681/Children-as-young-as-12-given-nicotine-patches-on-the-NHS.html

2. http://www.dailymail.co.uk/news/article-1200918/Boy-14-collapses-overdosing-nicotine-chewing-gum-handed-school.html

3. 20 pupils sent home from school with ‘toxic overdose’ after using nicotine spray
2015-03-28
http://schoolsimprovement.net/20-pupils-sent-home-from-school-with-toxic-overdose-after-using-nicotine-spray/
 

Pharmaceuticals - business

1. http://www.efpia.eu/uploads/Figures_Key_Data_2013.pdf
World pharma gross value ex-factory 2012: $858bn
41% in N America, 27% EU. UK market c. €14bn.
In the EU, manufacturers on average receive about 65% of the retail price, and government 10%. UK tax = 0% presc., 20% OTC.

2. Pharmaceutical industry gets high on fat profits
http://www.bbc.co.uk/news/business-28212223
Article that details the immense profits made by pharmaceutical corporations and how claims of high research costs are a smokescreen, obviously of little consequence due to the huge profits, and the fact they spend up to double the research costs on marketing. Some of the massive fines for criminal corruption and fraud are listed.

3. How pharma's claims of high research costs are exaggerated:
http://www.vox.com/2015/2/11/8018691/big-pharma-research-advertising
 

Pharmaceutical industry - criminal activity

1. Pharma & crime:
http://cfrankdavis.wordpress.com/2013/10/28/big-pharma-as-organised-crime/

2. Pharma crime analysis:
http://www.citizen.org/hrg2073

3. Pharmacia & Upjohn criminal fraud:
(FBI: largest criminal fine ever paid, to date)
http://www.fbi.gov/boston/press-releases/2009/bs091509b.htm

4. Pharmacia criminal fraud:
http://www.doj.state.wi.us/media-center/2013-news-releases/september-04-2013

5. Pfizer criminal fraud:
http://news.bbc.co.uk/1/hi/8234533.stm
http://www.medpagetoday.com/ProductAlert/Prescriptions/15808

6. Merck criminal fraud:
http://childhealthsafety.wordpress.com/2012/07/02/merck-vaccine-fraud-2nd-us-court-case-over-mmr-vaccine/
http://www.vaccinationcouncil.org/2012/06/25/scientists-sue-merck-allege-fraud-mislabeling-and-false-certificaion-of-mmr-vaccine-suzanne-humphries-md/

7. Abbott criminal fraud:
http://news.yahoo.com/abbott-laboratories-guilty-fraud-ordered-pay-1-5-212800951.html
https://www.taf.org/blog/racketeering-allegations-filed-against-abbott-laboratories

8. GSK criminal fraud, criminal corruption:
http://www.bbc.co.uk/news/world-us-canada-18673220

9. a. GSK corruption in China:
http://www.bbc.co.uk/news/business-23265958
http://www.boston.com/business/healthcare/2013/07/11/chinese-police-say-glaxo-employees-bribed-doctors/eQsW28TybsBSu99kzlEhTK/story.html
b. GSK bribery affair timeline:
http://www.telegraph.co.uk/finance/newsbysector/pharmaceuticalsandchemicals/10828571/Glaxo-China-bribery-allegations-timeline.html

10. Supreme Court rules that all generic drugs are exempt from civil actions (80% of US drug sales):
http://www.whiteoutpress.com/articles/q32013/supreme-court-rules-drug-companies-exempt-from-lawsuits/

11. Is big pharma addicted to fraud? (article)
http://www.forbes.com/sites/erikakelton/2013/07/29/is-big-pharma-addicted-to-fraud/

12. Wikipedia list of 20 largest US fines for criminal fraud and criminal corruption by pharmaceutical companies:
https://en.wikipedia.org/wiki/List_of_largest_pharmaceutical_settlements

13. list of notable fraud cases:
http://www.thelibertybeacon.com/2013/08/03/7-shameful-examples-of-big-pharma-fraud10967/

14. Johnson & Johnson criminal fraud:
http://www.healthline.com/health-news/policy-johnson-and-johnson-to-pay-record-settlement-in-suit-110413

15. Janssen criminal fraud:
http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm373499.htm

16. Pfizer: Chantix - evidence for >500 suicides; good list of links to sources:
http://america.aljazeera.com/watch/shows/america-tonight/america-tonight-blog/2013/11/21/fda-anti-smokingdrugchantixlinkedtomorethan500suicides.html

17. Takeda / Lilly fined $9bn for hiding cancer risks:
http://www.businessweek.com/news/2014-04-07/takeda-actos-jury-awards-6-billion-in-punitive-damages
http://www.bbc.co.uk/news/business-26933770
(The fines are likely to be reduced on appeal.)

18. Nicotine patches were invented by a fraudster (and are still promoted by fraudsters):
http://www.sec.gov/litigation/litreleases/lr15843.txt

19. GSK to be investigated by SFO:
http://www.bbc.co.uk/news/business-27597312

20. GSK pays settlements to 40-plus US states
http://www.ft.com/cms/s/0/b7edb00a-ec0a-11e3-a9e3-00144feabdc0.html

21. Pfizer Admits Bribery in Eight Countries
August 8th, 2012
http://www.corpwatch.org/article.php?id=15765

22. GSK $3bn fine
http://worldtruth.tv/glaxosmithkline-settles-fraud-case-for-3-billion

23. Big Pharma and Organized Crime - More Similar Than You Think
http://wakeup-world.com/2015/07/25/big-pharma-and-organized-crime-they-are-more-similar-than-you-may-think/

 

Pharmaceutical industry - funding

1. GSK funding:
http://www.sourcewatch.org/index.php/GlaxoSmithKline

2. RWJF grants to UCal / Glantz:
http://www.rwjf.org/en/grants/search.html?sort=&k=Glantz&d=&l=

3. Glantz funding:
http://www.plosmedicine.org/annotation/listThread.action;jsessionid=91D75662601DFC29C610F2305F59F817?root=5253

4. GSK finance
https://s3.amazonaws.com/iw-files/apps/2014/12/luxleaks/documents/208.html

 

Pharmaceutical industry - medical malpractice

1. Experts Say Medical Practice Corrupted by Pharmaceutical Industry:
http://www.hg.org/article.asp?id=31773

2. A document addressing the problem of medical professionals' COIs:
http://www.badscience.net/2013/12/heres-our-letter-to-the-gmc-about-addressing-systemic-failures-in-the-medical-profession/

3. Dr P Rost: how pharma buys the medical establishment:
http://www.youtube.com/watch?v=te-nAxn-K3M

4. Medical malpractice:
http://www.forbes.com/sites/larryhusten/2014/01/15/medicine-or-mass-murder-guideline-based-on-discredited-research-may-have-caused-800000-deaths-in-europe-over-the-last-5-years/

5. Half of drugs prescribed in France "useless or dangerous", "causing 20,000 deaths a year":
http://www.theguardian.com/world/2012/sep/14/french-doctors-drugs-useless-dangerous

6. Unhealthy Pharmaceutical Regulation: Innovation, Politics and Promissory Science
Courtney Davis, John Abraham
Palgrave Macmillan 2013
http://books.google.ca/books?id=CaREAgAAQBAJ&source=gbs_navlinks_s
http://books.google.ca/books?id=CaREAgAAQBAJ&printsec=frontcover#v=onepage&q&f=false

7. Doctors may have to declare links to drug companies
Telegraph, July 2015
http://www.telegraph.co.uk/news/nhs/11760922/Doctors-may-have-to-declare-links-to-drug-companies.html
Apparently it has come as news to some people that the UK health services are corrupt.

8. Dr. Peter Rost, ex-VP of Pfizer, comments om pharmaceutical industry marketing practices:
http://www.collective-evolution.com/2015/07/07/pfizer-vice-president-blows-the-whistle-tells-the-truth-about-the-pharmaceutical-industry/


 

Corruption issues attributed to pharma
1. EU - more on Dalli:
http://www.maltatoday.com.mt/en/newsdetails/news/courtandpolice/Gayle-Kimberley-questioned-by-police-over-Dalligate-20131206

2. Jeremy 'pharma' Hunt:
http://www.trendingcentral.com/jeremy-hunts-new-war-e-cigarettes/

3. Pharmaceutical industry helps determine NHS policy:
http://www.independent.co.uk/news/uk/politics/revealed-big-pharma-links-to-nhs-policy-with-senior-mps-saying-medical-industry-uses-wealth-to-influence-government-9120187.html

4. Dr Peter Rost, former vice president of Pfizer describes how pharma buys universities:
https://www.youtube.com/watch?v=TrCizlAOBAo
"And that's how you influence the medical establishment - simply with money."

5. More on Dalligate
http://euobserver.com/smoke-and-mirrors/126125
Dalli claims that post-Dalli changes in the TPD that continue to allow sales of chewing tobacco, snuff and ecigs (his version banned them all) are 'pro-tobacco industry' when this is the opposite of the truth: cigarette sales are threatened by these products (as they are all in essence THR, since they are alternatives to smoking). Dalli's TPD removed all forms of tobacco and nicotine products and therefore his version very strongly protected cigarette sales. Dalli, again, argues against his removal for corruption by stating the opposite of the truth - a device that has always worked very well for the pharmaceutical and cigarette industries, who Dalli strongly protected to the best of his ability until his removal from office. Unfortunately we are still left with his most successful smoking-protection ploy of all: the Snus ban, which has by now killed approaching a million in Europe but more importantly (and profitably) made millions ill - a measure of its success and indeed the whole point of the ban.

6. Alleged drug company corruption in Chicago:
http://mobile.businessweek.com/articles/2014-11-14/drug-companies-didnt-want-you-to-see-allegations-of-lavish-spending

7. Using Doctors With Troubled Pasts to Market a Painkiller
http://www.nytimes.com/2014/11/28/business/drug-maker-gave-large-payments-to-doctors-with-troubled-track-records.html?smid=tw-share&_r=0

8. CDC, WHO and Big Pharma: A Dangerous Network of Corruption
http://anticorruptionsociety.com/2015/03/02/cdc-who-and-big-pharma-a-network-of-corruption/

9. The money trail: how government, pharma and tobacco all make money from smoking and all support the Tobacco Control industry:
http://tctactics.org/index.php/Money

10. Useful links for pharmaceutical idustry influence on government:
https://brainyfurball.wordpress.com/2015/05/17/fire-in-the-madhouse/

11. More on Dalli, from Malta
https://daphnecaruanagalizia.com
https://daphnecaruanagalizia.com/2015/05/the-conspiracy-against-him-grows-john-dalli-loses-case-in-european-court-of-justice/

12. FBI investigates Dalli's family of thieves and swindlers:
http://www.independent.com.mt/articles/2015-05-10/local-news/FBI-Maltese-police-asked-to-investigate-company-involved-in-John-Dalli-s-Bahamas-trip-6736135258

13. Big Pharma = Big Bias
Rosner, May 2015
http://www.toyourhealth.com/mpacms/tyh/article.php?id=2117

14. More on Dalligate
http://velvetgloveironfist.blogspot.co.uk/2015/03/where-are-john-dallis-supporters-now.html

15. Confessions of a pharma sales rep
http://www.collective-evolution.com/2015/03/18/we-are-trained-to-misinform-ex-big-pharma-sales-rep-speaks-out-about-the-deception-in-the-pharmaceutical-industry/

 

Pharmaceutical industry - perversion of clinical trials

CTs and RCTs are easy to rig, and books have been written on the dozens of ways to accomplish it. The junk science resulting is used to sell more drugs or get legislation that defeats competitors with better, safer, cheaper products.

1. Editor In Chief Of World’s Best Known Medical Journal: Half Of All The Literature Is False
http://www.collective-evolution.com/2015/05/16/editor-in-chief-of-worlds-best-known-medical-journal-half-of-all-the-literature-is-false/
Lancet and NEJM editors say clinical research is falsified.

2. Ben Goldacre on how pharma conceals bad trial results
http://www.badscience.net/2012/10/the-abpi-claims-that-all-the-problems-in-my-book-are-historical-this-claim-is-simply-untrue/

 

Pharmaceutical industry - propaganda

1. Pharma foundations and front groups:
http://www.forces.org/News_Portal/news_viewer.php?id=2303

 

Pharmaceutical industry - protecting cancer

The pharmaceutical industry clearly acts to protect the sales of cancer treatment drugs, which are among its most profitable. For example we know from US residents' bills that the average cost of one course of treatment is over $20,000 and can reach $46,000 for some common types of cancer. The best way to protect cancer drug sales, currently, is to block THR as this is the only real threat to smoking. Smoking is a first-class provider of cancer patients for pharma and its front groups, who obviously need to protect cancer in order to get paid.

1. How much does chemotherapy cost?
http://www.nerdwallet.com/blog/health/2014/09/17/how-much-does-chemotherapy-cost/
An average course of threatment is $20,000 in the USA. Some treatments can cost more than double this.

2. More lies from a cancer org
http://www.sundayworld.com/style/health/e-cigarettes-nicotine-addiction-smoking-quit-irish-cancer-society
How the Irish Cancer Society is prepared to lie in order to protect its funders and protect cancer. ICS has a long list of pharmaceutical corporate funders including Pfizer, GSK, Roche, Novartis and several more. Strangely, these names are among the firms with the largest fines for criminal offences in the world, including criminal corruption.
http://velvetgloveironfist.blogspot.co.uk/2015/04/the-irish-cancer-societys-hard-sell.html
C Snowdon analyses the corruption.

3. ACS promotes cancer
M Siegel, 2015-04-23
http://tobaccoanalysis.blogspot.co.uk/2015/04/why-is-american-cancer-society.html

4. Cancer charity corruption
http://www.reuters.com/article/2015/05/19/us-ftc-charities-idUSKBN0O420I20150519
US government charges four cancer charities with misusing more than $187 million in donations - FTC charges criminally fraudulent cancer charities: one raised $86.8 million for 'charity' but assigned just 1 percent to charitable purposes.

 

Pharmaceutical industry - regulation

1. How failure of regulation in the pharmaceutical industry helped cause an epidemic:
www.economist.com/news/books-and-arts/21660072-terrible-story-ongoing-drug-epidemic-poppy-love

 

Pharmaceutical industry - working against ecigs

1. Glaxo Memo Shows Drug Industry Lobbying on E-Cigarettes
http://www.bloomberg.com/news/articles/2014-02-19/glaxo-memo-shows-drug-industry-lobbying-on-e-cigarettes

 

Pharma-smoking - the profit machine

1. Report: US pharmaceutical / medical industry earns $170 billion per annum from smoking:
http://www.ajpmonline.org/article/S0749-3797%2814%2900616-3/abstract

 

Pharma-tobacco commercial links

1. Altria-Fertin
http://www.fertin.com/aboutus/companyfacts/Pages/default.aspx
http://www.tobaccotoday.info/2012/01/28/altria-partners-with-fertin-pharma/



Pharmacy / Chemists

1. How your UK chemist will now tell you a pack of lies, and is clearly guilty of medical negligence:
http://www.redheadfullofsteam.com/mr-pharmacist-can-you-help-me-out-today/

 

Pharmaceutically-caused mortality

1. Pfizer settles 2,700 cases out of court for >$273m, in US Chantix class action:
http://blog.al.com/spotnews/2013/07/pfizer_enters_final_settlement.html

2. Zyban associated with multiple mortalities in UK:
http://schoolofdolphins.wordpress.com/2014/01/21/smokers-die-after-taking-zyban-cure/

3. The murder drug:
http://www.ecigarettedirect.co.uk/ashtray-blog/2011/04/the-new-anti-smoking-strategy-get-mentally-ill-smokers-to-kill-themselves-and-their-families.html